Science and Technology) 2007-2011 This work was partly supported

Science and Technology) 2007-2011. This work was partly supported by a research grant for Higashiosaka City. References 1. Tarhini

AA, Agarwala SS: Cutaneous melanoma: available therapy for metastatic disease. Dermatol Ther 2006, 19:19–25.PubMedCrossRef 2. Howe HL, Wingo PA, Thun MJ, Ries LA, Rosenberg HM, Feigal EG, Edwards BK: Annual report to the nation on the status of selleckchem Cancer (1973 through 1998), featuring cancers with recent increasing trends. J Natl Cancer Inst 2001, 93:824–842.PubMedCrossRef 3. Woodhouse EC, Chuaqui RF, Liotta LA: General mechanisms of metastasis. Cancer 1997, 80:1529–1537.PubMedCrossRef 4. Van Noorden CJ: Proteases and protease inhibitors in cancer. Acta Histochem 1998, 100:344–354.PubMed 5. Sternlicht MD, Werb Z: How matrix metalloproteinases find more regulate cell behavior. Annu Rev Cell Dev Biol 2001, 17:463–516.PubMedCrossRef 6. Coussens LM, Fingleton B, Matrisian LM: Matrix metalloproteinase inhibitors and cancer: trials MM-102 in vitro and tribulations. Science 2002, 295:2387–2392.PubMedCrossRef 7. Egeblad M, Werb Z: New functions for the matrix metalloproteinases in cancer progression.

Nat Rev Cancer 2002, 2:161–174.PubMedCrossRef 8. Danen EH, Yamada KM: Fibronectin, integrins, and growth control. J Cell Physiol 2001, 189:1–13.PubMedCrossRef 9. Ingber DE: Integrins, tensegrity, and mechanotransduction. Gravit Space Biol Bull 1997, 10:49–55.PubMed 10. Chrenek MA, Wong P, Weaver VM: Tumour-stromal Etomidate interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation. Breast Cancer Res 2001, 3:224–229.PubMedCrossRef 11. Hartstein ME, Grove AS Jr, Woog JJ: The role of the integrin family of adhesion molecules in the development of tumors metastatic to the orbit. Ophthal Plast

Reconstr Surg 1997, 13:227–238.PubMedCrossRef 12. Moretti S, Martini L, Berti E, Pinzi C, Giannotti B: Adhesion molecule profile and malignancy of melanocytic lesions. Melanoma Res 1993, 3:235–239.PubMed 13. Grünler J, Ericsson J, Dallner G: Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins. Biochim Biophys Acta 1994, 1212:259–77.PubMed 14. Elson CE, Peffley DM, Hentosh P, Mo H: Isoprenoid-mediated inhibition of mevalonate synthesis: potential application to cancer. Proc Soc Exp Biol Med 1999, 221:294–311.PubMedCrossRef 15. Pronk GJ, Bos JL: The role of p21ras in receptor tyrosine kinase signalling. Biochim Biophys Acta 1994, 1198:131–147.PubMed 16. Hall A: Rho GTPases and the actin cytoskeleton. Science 1998, 279:509–514.PubMedCrossRef 17. Goldstein JL, Brown MS: Regulation of the mevalonate pathway. Nature 1990, 343:425–430.PubMedCrossRef 18. Nonaka M, Uota S, Saitoh Y, Takahashi M, Sugimoto H, Amet T, Arai A, Miura O, Yamamoto N, Yamaoka S: Role for protein geranylgeranylation in adult T-cell leukemia cell survival. Exp Cell Res 2009, 315:141–150.PubMedCrossRef 19.

Comments are closed.