Summary of Background Data. Synovial chondromatosis is an uncommon disorder characterized by the formation of multiple cartilaginous nodules in the synovium of a facet joint. It most commonly affects large joints. Synovial chondromatosis in the spine is rare and there is no previous report of associated lumbar radiculopathy.

Methods. A 24-year-old woman presented with low back pain and right sciatica lasting

5 months. There was no objective weakness. Computed tomography scans showed multiple calcified nodules anterior and medial to the right apophyseal joint of L5-S1 and extending into the spinal canal. Magnetic resonance imaging showed a lobulated, heterogeneous enhancing extradural mass arising from the anteromedial aspect of ABT-263 in vivo the right L5-S1 facet joint. The MLN4924 lesion was removed in multiple pieces with curette after exposure of the corresponding intervertebral space through a conventional interlaminar approach. The histologic examination showed nodules of hyaline cartilage beneath the synovial cell lining.

Results. The patient was completely free of low back pain and right sciatica 5 days after the surgery. All neurologic

tests were normal from that point onwards.

Conclusion. Synovial chondromatosis may compromise lumbar nerve roots when it extends into the spinal canal from the facet joint. Although synovial chondromatosis of the lumbar spine is rare, it should be included in the differential diagnosis of radiculopathy.”
“We investigated seven distance measures and 14 similarity coefficients in a set of observations of variables of the ‘yellow’ passion fruit plant (Passiflora edulis Sims), submitted to multivariate analyses (distance, projection and grouping). Fourteen genotypes were characterized, based on DNA amplification with 16 random amplified

polymorphic DNA primers and the assessment of nine fruit physical-chemical Bcr-Abl inhibitor descriptors. The distance measurements and the similarity coefficients were compared by the Spearman correlation test, projection in two-dimensional space and grouping efficiency, using five grouping methods; the genotype ranking varied with the different techniques. Coler-Rodger distance measures, Euclidean distance square measures and Yule similarity coefficients proved to be inadequate for projection in two-dimensional space or for grouping matrices. Regardless of the origin of the distance matrix, the unweighted pair group method with arithmetic mean grouping method proved to be the most adequate. The various distance measurements, similarity coefficients and grouping methods gave different values of distortion, cophenetic correlation and stress; they influence the characterization of genetic variability and this should be taken into account for studies of yellow passion fruit plants.”
“Bone regeneration has long been a major focus for tissue engineers and the importance of vascularization to the bone regeneration process has been well documented.