In all cases, p-values less than 0.05 were accepted to determine statistical significance. All analyses were performed using SPSS, Version 16. Results Participants Twenty four of the 32 recruited subjects completed both exercise trials. The study subjects were aged 25.2 ± 3.6 years with a mean body mass of 87.1 ± 14.5 kg and stature of 177.8 ± 6.9 cm. The 24 study PF-562271 subjects were confirmed to satisfy the inclusion

criteria of consistent participation in resistance training during the six months prior to this study. Eight of the recruited subjects declined to participate in the research trial past the two familiarization test sessions. The intense nature of this exercise protocol appears to be related to the relatively high rate of attrition (25%). All statistical analyses are based on the data collected from the 24 subjects that completed both sprint test sessions. Planned sample size (32) was based on an estimated 10% dropout rate establishing

a 0.75 level of power with a 0.25 predicted effect size. The reduced number of subjects limited statistical power to the 0.65 level, and is seen as a limitation of the present study as potential LB-100 solubility dmso differences between conditions may not have been detected. Lifestyle Records Dietary log data Macronutrient intake values for both study conditions are presented in Table 1. Dietary intake data for protein (g), carbohydrates (g), and fats (g) as well as total calories were analyzed to determine daily averages Galeterone which were compared between study conditions. Analysis indicated that there were no significant differences in these nutrient values for the three-day period preceding each of the two exercise trials. Table 1 Nutritional recall information placebo GPLC   Placebo GPLC Protein (gr) 179.8 ± 74.6 184.9 ± 75.7    % total cals 29% 30% Carbohydrates (gr) 272.6 ± 145.1 254.4 ± 130.0    % total cals 44% 42% Fats (gr) 73.8 ± 30.2 75.7 ± 32.6    % total cals 27% 28% Total Calories

2482.2 ± 739.9 2434.1 ± 761.0 Exercise log data The exercise training records provided information related to the PF-4708671 molecular weight volume of resistance training performed during the seven day supplementation period. Subjects were asked to record the number of sets and repetitions performed for each training exercise per session. Resistance training movements were classified, by investigators, based on upper versus lower extremity movements and based on compound versus single-joint exercises, thus establishing four exercise categories: upper extremity compound, upper extremity single-joint, lower extremity compound, and lower extremity single-joint. Table 2 provides a comparison of the training volume between placebo and GPLC conditions relative to the exercise categories. Analyses revealed no significant differences in the number of sets or repetitions between conditions in any of the four exercise categories (p > 0.05). Table 2 Exercise training volume placebo GPLC     Placebo GPLC Upper Extremity Sets 38.5 ± 16.8 37.9 ± 17.