Conclusion: The present study showed that incidence of ulcerative colitis is increasing. There was no significant change in the clinical features and symptoms

including bloody diarrhea and abdominal pain of ulcerative colitis patients between two study periods. However, the proportion of proctitis has been increasing nowadays. Immunmodulator was used more frequently in 2012 and variable promising medications such as biologics were newly introduced for the treatment of severe ulcerative colitis. Key Word(s): 1. ulcerative colitis; 2. change; 3. clinical; Presenting Author: CHAN SEO PARK Additional Authors: BYUNG IKBYUNG IK, KYEONG OKKYEONG MG 132 OK, SI HYUNGSI HYUNG, JUN SUKJUN SUK Corresponding Author: SI HYUNGSI HYUNG Affiliations: Yeungnam University College of Medicine Objective: Inflammatory bowel disease (IBD) is an idiopathic, chronic inflammation of large and small bowel characterized by episode of relapse and remission. The relapse CDK inhibitor is not predictable although several factors have been suggested. The aims of the present study were to assess

and compare the possible causes of the symptom relapse in patients and parents aspect. Methods: Among 107 young IBD patients under 35 years, 26 patients who experienced recent (<3month) relapse filled up the questionnaire with their parents at the same time. The baseline characteristics and clinical manifestation were reviewed. We also assess the most commonly perceived causes of the relapse and compared among the patients and parents. Results: The median age of the patients was 22.5 ± 4.71 years and male to female ratio was 17:9. Crohn's disease was diagnosed in 23 patients and the other 3 patients were ulcerative colitis and mean disease duration was 39.8 ± 30.3 months. 69.2% of the patients felt MCE公司 stress before relapse and 42.3% of the patients showed non-adherence to their maintenance treatment. In case of parents, 57.7%

thought that there was stress to their offspring before relapse. 42.3% of the parents thought that their children were not adherent to medication. Non-adherence to medication showed 100% and stress 73.1% agreement between patients and parents, Stress was considered as the most common possible main causes of the relapse in both. The agreement rate in main cause of relapse among them was 57.7%. Conclusion: Stress was most commonly noted before symptom relapse in young IBD patients. Both patients and parents considered it as the main cause of the relapse, however, discordance rate between patients and parents was 42.3%. This result suggested that there might be a considerable difference in the understanding of the disease and between young IBD patients and parents. Key Word(s): 1. Discordance; 2. IBD; 3. patients; 4.