Competing interest Crizotinib ALK The authors declared that they had no competing interests. Authors�� contribution HMA AM MME SS did analyzing and manuscript drafting. MHR did review critically and also supervise. AF MF AA AMHK did data collection and checks the manuscript. All authors check and approve the final version. Acknowledgement We really appreciate all participants of this study.
The increasing prevalence of childhood obesity has become a growing matter of public health concern worldwide. Obesity has increased from 4.2% in 1990 to 6.7% in 2010 worldwide and is expected to reach 9.1% in 2020 [1]. The risk is more for children in industrialized countries where the prevalence has increased more than twice in the past three decades [2]. In 2010, 43 million children were estimated to be obese worldwide, out of whom, 35 million (81.
4%) were from developing countries [1]. The estimated prevalence of childhood obesity in Africa in 2010 was 8.5% and is expected to reach 12.7% in 2020 [1]. North Africa is the region with highest prevalence of childhood obesity in Africa [3]. Few studies have been conducted on the prevalence of Inhibitors,Modulators,Libraries obesity among primary school children in Tanzania[4-6]. In a study conducted in Dodoma and Kinondoni, Mosha et al. showed that the prevalence of obesity among children aged 6�C9 years was 5.6% and 6.3% respectively [5]. A similar low prevalence of child obesity (5.3%) was also reported by Chillo et al. in a study conducted in Dar es Salaam and Morogoro regions [4]. Genetic and environmental factors have been documented as potential causes of obesity [7,8].
The rising prevalence Inhibitors,Modulators,Libraries of childhood obesity in developing countries is attributed to the growing urbanization, transition towards high caloric western diet of refined and fast foods and sedentary lifestyle [9,10]. Tanzania is not spared by the consequences Inhibitors,Modulators,Libraries of globalization, and profound societal changes have taken place especially in urban settings [11,12]. Leisure time activities are increasingly sedentary. Entertainments such as television, video and computer games are also widely and easily accessible. Hours spent on viewing television and computer usage is associated with increasing BMI among children [13]. Walking to and from school and morning joggings provided a potentially Inhibitors,Modulators,Libraries important opportunity for establishing Inhibitors,Modulators,Libraries daily physical activity among primary school children [14].
Literature from both, developed and developing countries have documented association between childhood obesity with many adverse health Brefeldin_A effects, ranging from hyperlipidemia, hypertension, respiratory disorders, glucose intolerance and type 2 diabetes mellitus, depression and low self-esteem to social discrimination [15-19]. All these adverse effects point to the necessity of preventing childhood obesity.