(C) 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.”
“Persisting Symptoms after Elective Sigmoid Resection for Sigmoid Diverticulitis\n\nIn the past, sigmoid resection in patients with recurrent sigmoid diverticulitis was typically recommended after the second episode. In recent years, this practice has been questioned as well as abandoned in favor of a more individual decision making. After elective sigmoid resection for diverticulitis, however, approximately a quarter of all patients report persistent or new-onset symptoms. In the minority of cases, see more actually genuine recurrent diverticulitis plays a role,

in which the height of the anastomosis is a determining factor. Often patients report about symptoms suggestive of irritable bowel syndrome, and studies in the recent years also show an overlap of

irritable bowel syndrome and diverticular disease. Recent studies suggest that visceral hypersensitivity and markers SRT2104 of inflammation are correlated in patients with symptomatic diverticular disease. In conjunction with predisposing factors such as obesity, these conditions may be a key reason for persistent complaints. Therefore, on the one hand, it will be up to the physician to identify those patients who are at high risk for complications and have a high probability of remaining symptom-free postoperatively. On the other hand, patients who will selleck screening library most likely not benefit from surgery should be directed towards other treatment modalities.”
“Background: Bovine cutaneous fibropapillomas are benign hyperproliferative lesions induced by Bovine Papillomaviruses (BPVs). Bcl-2 is an important anti-apoptotic protein which is expressed in several cancer types. In contrary, p53 is a tumour suppressor protein that mediates cell cycle arrest, apoptosis and senescence in response to cellular stresses. Findings: Here, we investigated immunohistochemically and biochemically, the expression

of bcl-2 and p53 in a subset of BPV positive fibropapillomas and bovine normal skin. Normal skin samples showed a weak signal for both proteins in the cytoplasm of the basal cells. Nine out of twelve (75%) tumour samples stained positive for bcl-2 throughout basal and parabasal layers, with most of cells showing strong cytoplasmic immunoreactivity. Nine out of twelve (75%) fibropapillomas were found to be positive for p53 expression, showing a strong cytoplasmic and perinuclear staining of p53 protein mainly in the basal and parabasal layers. Conclusions: Our data reveal an altered bcl-2 and p53 immunoreactivity in bovine cutaneous fibropapillomas, suggesting involvement of these two proteins in the cutaneous neoplastic transformation through an impaired apoptotic process.”
“Aim This study aimed to compare the effect of extended margin and conventional bleaching trays on tooth bleaching and tooth sensitivity.