At >= 2 years after intervention, aneurysm diameter was reduced in 62% of patients, 33% had no change, and 5% had a diameter enlargement. The stent graft complication rate during follow-up was 8.4%, the device fracture rate was 1.4%, and the device migration rate was 7%. The 5-year survival rate was 62.4%, with follow-up in 96.8% of the patients.
Conclusion: Endovascular repair has promising results in the descending
thoracic aortic region, although some stent grafts and their delivery systems can PF-02341066 price still be improved. Additional commercial developments and available stent grafts designed for use in the distal arch are urgently needed. (J Vasc Surg 2008;48:24S-29S.)”
“OBJECTIVE: Trigeminal schwannomas (TS) are benign tumors that are managed by surgical resection and/or stereotactic radiosurgery. Most radiosurgical series report results using the gamma knife. The CyberKnife (Accuray, Inc., Sunnyvale, CA) is a frameless, robotic
stereotactic radiosurgical system. In this series, we report our experience using the CyberKnife in the treatment of TS.
METHODS: We retrospectively reviewed the medical records and diagnostic imaging in 13 consecutive patients with TS who were treated with the CyberKnife from 2003 to 2007. Seven patients had a previous surgical resection. The mean tumor volume was 6.3 mL (range, 0.39-19.98 mQ, and the mean marginal dose was 18.5 Gy. Six of the tumors were treated in a single session. The mean clinical follow-up period was 21.8 months (range, 7-53 months).
RESULTS: In this series, the tumor control rate was
100%. The average reduction in tumor volume was 45% (range, Selleck JQ-EZ-05 14-98%). A modest improvement in facial pain was noted in 4 of the 6 patients who presented with this symptom. One patient had improvement in facial numbness, and another had improvement in pretreatment headaches. CRM1 inhibitor One patient developed jaw weakness and facial dysesthesia, and another patient developed asymptomatic radiation necrosis.
CONCLUSION: Although the length of follow-up is limited, we report our initial experience with CyberKnife treatment of TS. Our results demonstrate tumor control rates and clinical outcomes that parallel those of previous reports using gamma knife radiosurgery; however, long-term follow-up studies are needed.”
“Objective: This study reports the initial clinical results and experience with the planning of branched stent grafts in high-risk patients with thoracoabdominal aortic aneurysms (TAAAs).
Methods: High-risk patients with TAAAs were considered for this study. Based oil evaluation with computed tomography angiography (CTA), 21 custom-made branched stent grafts were designed for the selected patients. Two patients had associated bilateral aneurysms of the common iliac arteries, so an iliac branched device was also used.
Results. Between August 2006 and April 2008, 23 patients (10 women, 13 men) were selected to undergo endovascular TAAA repair. Mean age was 72 years old.