30 The zinc dose used in this study is another important variable to consider, as it may have been insufficient to achieve the expected effect, as the recommended dose for treatment and prevention of DD and ARI is 10 to 20 mg/day.12 Larger amounts of zinc were not offered as the objective was to evaluate the supplementation

through the use of sprinkles with 5 mg/zinc, whose recommended use is of one sachet/day.15 Therefore, in a healthy population, zinc supplementation with 5 mg/day may not be as effective in the prevention of infectious diseases. Regarding acceptance, sprinkles appear to be an efficient way of supplementing zinc intake, as well as other TSA HDAC mw micronutrients. The data analyzed in this study reflect an acceptance > 90%. It is noteworthy the fact that the sprinkles were added to the food that was best accepted by the participants and, as they provide almost no change in

flavor or color of preparations, their consumption may be associated with the acceptance of the food offered to the children. Other studies that assessed the acceptance of sprinkles16 and 17 also showed similar results, suggesting they are a good option to fight micronutrient deficiencies, especially because they do not alter the organoleptic characteristics of food. Based on the present study, it can be concluded that zinc supplementation through the use of sprinkles had no impact in reducing the incidence of DD and ARI, nor influence on the nutritional status of the study population. However, the good acceptance Akt inhibitor of sprinkles offers a new form to administer supplemental micronutrients, representing an innovation in the management of children’s nutritional deficiencies. The sprinkles were donated by Emory University, Atlanta, GA, USA. The authors declare no conflicts of interest. “
“Environmental Glutamate dehydrogenase tobacco smoke (ETS) is associated with a higher prevalence of asthma in adolescents, and with more severe

forms in children. Passive exposure to tobacco smoke is common, and its damaging effects on health have been well-known for decades.1 However, the magnitude of the problem worldwide is poorly described2. Childhood asthma is one of the diseases that most contributes to the health costs arising from passive smoking.2 It was estimated that 603,000 deaths were attributable to second-hand smoke in the year 2004, representing 1% of world mortality, of which 28% occurred in children.2Although the higher prevalence and severity of childhood asthma due to ETS appears to be well-established,3, 4, 5 and 6 other studies report that ETS is not associated with a higher prevalence of asthma in children.7, 8 and 9 The aim of the present study was to analyze the prevalence of asthma symptoms in children and adolescents in this community, according to the passive exposure to smoking by the parents.