, 2009, for further selleckbio details). Participants were selected as part of the TTURC:NEFS using a multistage sampling procedure that oversampled families in which multiple siblings participated. Screening questionnaires were mailed to 4,579 of the 15,721 Boston and Providence TTURC:NEFS offspring who survived until age 7. Of the 3,121 questionnaires returned (68.2%), 2,271 were selected for participation as meeting eligibility criteria for one or more of the three substudies of the overall TTURC:NEFS project. Of these, we enrolled 1,674 offspring (73.7%); the remaining subjects either could not be relocated or scheduled, or refused to complete the full study assessment. Data from 49 individuals were excluded from the final sample because they received a pilot version of the survey (n = 11) or because of problems with the interview administration (n = 38), resulting in a final interviewed sample of 1,625 adults.

We report here only on those who were currently smoking at the time of the interview and who completed all diagnostic and smoking assessments and the MPQ. Current smokers were defined as individuals who had smoked at least 100 cigarettes and who were currently smoking cigarettes at least 1 day/week. We excluded smokers who currently smoked less than once per week and those who currently smoked only cigars and/or pipes. Of the 1,625 participants, 497 (30.6%) reported current cigarette smoking. The MPQ and WISDM were self-administered after the in-person interviews and were completed by 296 (59.6%) of current smokers. Men��s completion rate was significantly lower than women��s (50.

3% vs. 65.3%, ��2[1, N = 497] = 10.9, p < .001). Completion rate was not significantly associated with age, education, marital status, race/ethnicity, or psychiatric disorder history. The final analytic sample of 296 current smokers was 67.9% women and 37.5% were married. The mean age was 38.8 years (SD = 1.9, range = 35�C43). The sample was 81.8% non-Hispanic White, 8.4% Black, 1.7% Hispanic/Latino, and 8.1% of other backgrounds. Five percent of participants completed less than high school education, 27.7% completed high school or GED only, 48.6% completed some postsecondary education, 8.9% completed college, and 2.7% completed a graduate degree. The sample included 249 subjects with no siblings in the analytic sample, 22 sibling pairs, and 1 sibling trio from a total of 272 families. Participants smoked an average of 17.6 (SD = 10.7, range = 1�C60) cigarettes/day, their mean score on the FTND was 4.25 (SD = 2.67), and 52.1% had a current diagnosis of tobacco Carfilzomib dependence. Measures Smoking measures Smoking histories were obtained by the Lifetime Interview of Smoking Trajectories and the Quitting Methods Questionnaire, developed for the TTURC:NEFS.