Results. The mean detection and pain thresholds showed a significant increase resulting from the

relaxing DSB, whereas no significant changes LY294002 datasheet of these thresholds were found associated with the attentive DSB. The mean skin conductance levels indicating sympathetic activity decreased significantly during the relaxing DSB intervention but not during the attentive DSB. Both breathing interventions showed similar reductions in negative feelings ( tension, anger, and depression).

Conclusion. Our results suggest that the way of breathing decisively influences autonomic and pain processing, thereby identifying DSB in concert with relaxation as the essential feature in the modulation of sympathetic arousal and pain perception.”
“Phytochemical investigation of the aerial parts of Ligularia thomsonii has led to the isolation of three new phenylpropanoid glucosides ligularoside I (1), ligularoside II (2) and ligularoside III (3) along with nine known compounds; cinnamic acid (4), 3-phenylpropanoic acid (5), 3,4,5-trihydroxybenzoic acid (6), 4-hydroxybenzoic acid (7), p-coumaric acid (8), caffeic acid (9), 3,4-dihydroxybenzoic acid (10), kaempferol 3-O-beta-D-glucopyranoside (11) and 3,5-di-O-caffeoylquinic acid (12), hitherto unreported from L. thomsonii. Their chemical structures were elucidated by spectroscopic analysis and chemical transformation.

All these compounds were tested for antioxidant activity using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 9, 10 BI 2536 chemical structure and 12 showed significant antioxidant activity against DPPH radicals with IC50 of 19.6, 23.3 and 8.9 mu m,

respectively. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.”
“Purpose: The aim of this study was to explore patients and health professional’s perceptions of follow-up service provision following treatment for ovarian cancer. In the United Kingdom, where this study took place, ovarian cancer is the most common gynaecological cancer in women. The causes are unknown, symptoms are often vague and most cases are diagnosed at an advanced learn more stage. There is a high likelihood of disease progression and little evidence on the benefits of routine follow-up after treatment for gynaecological cancer.

Method: Two focus groups were conducted with patients (n = 6) and health professionals (n = 7) at a hospital in North-West England.

Results: From the patient group, three main themes emerged: reassurance, the need for support and information, and alternative approaches to follow-up care. Three main themes emerged from the health professional group: patient attendance at outpatient clinics to monitor for disease progression; the need to modernise the current system: and patients should be encouraged to self-manage their disease.

Conclusions: There were similarities and differences in perceptions of follow-up care procedures between the two focus groups.